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Mercaptopropane sulfonic acid (MPS) was used as a model compound to investigate the electrochemical response in aqueous solution

60,61,62 RNase H-dependent ASOs, such as gapmers, bind to complementary mRNA, recruit RNase H to cleave mRNA, and thus block translation of the target gene

Possible risks if self-used incorrectly include mineral imbalance (copperzinc), skin irritation or hypersensitivity, and incorrect dosing with injectables

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