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Sources Chiang PK, Gordon RK, Tal J, Zeng GC, Doctor BP, Pardhasaradhi K, McCann PP

The molecule was first identified and studied by the Sikiric research group in Croatia starting in the early 1990s, and the bulk of the preclinical evidence base comes from more than three decades of rat and rodent studies showing consistent tissue-repair, anti-inflammatory, and gastroprotective effects

For these individuals, methylcobalamin may provide superior results

doi: 10.1091/mbc.E04-03-0224

Other risk factors include age over 50 (reduced gastric acid impairs absorption), proton pump inhibitor use, prior gastric surgery, and Type 1 diabetes

Studies were terminated when the mean diameter of the tumor reached 15mm