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This dose-tolerability relationship provides useful guidance for clinical protocol development

[DOI] [PubMed] [Google Scholar] 21.Harvold E.P., Tomer B.S., Vargervik K., Chierici G

Not for the way TB-500 is marketed

2014 Nov 20;9(11):e110598

Batch: GF-AOD10-B241 Key analytical results include: Assay Content: 11.48 mg Identification Retention Time: 0.986 Identification Spectrum: 995 Purity: 99.7 percent Bacterial Endotoxins: below 0.001 EU per mg Total Aerobic Microbial Count: not detected Total Yeast and Mold Count: not detected Independent heavy metal screening confirmed no detectable levels of arsenic, cadmium, cobalt, lead, nickel, mercury or vanadium

however, these studies frequently lack methodological rigor, appropriate controls, and adequate statistical power to confirm efficacy