They are not approved for human consumption, medical treatment, or veterinary use
The mechanism of action isnt well understood, but its believed it doesnt affect the tendon tissue cells directly, but rather that either works by activating other repair cells that can help tendons or ligaments or making the human growth factor receptor on the repair cells more sensitive (3)
Ruff MR, Wahl SM, Pert CB
This is of great importance, especially in the case of apple seeds, in which cyanogenic compounds are metabolised (Krasuska et al
Nausea (28%), diarrhea (23%), constipation (17%), and vomiting (12%) at the 12mg dose are the most commonly reported
I believe it is good practice to bolster your glutathione ratio with an oral form anytime you are going to spend extended time outdoors, or if you live in a particularly tick-heavy environment during the spring, summer, and fall months