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Tamoxifen induces apoptosis in P-gp expressing cells To determine if tamoxifen-induced collateral sensitivity of drug resistant cells is due to enhanced apoptosis, AuxB1 and CHO R C5 cells were treated with tamoxifen for 24 h and then examined for the presence of apoptotic cells using FITC-conjugated annexin-V and cell staining with Hoechst Dye
Use of this product is therefore not intended to compensate for diagnosis, treatment, cure, or mitigation of medical conditions and must not substitute the obtaining of medical advice from a registered health professional for any health or health-related conditions
J Clin Invest 2006
For repeated measures data, two-way repeated measures ANOVA (2-way RM ANOVA) was employed
por Alexander M
Front Pharmacol 14:1210393 Fisher SP, Sugden D (2010) Endogenous melatonin is not obligatory for the regulation of the rat sleep-wake cycle
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