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finally, CS-induced increased mediators with vasoconstrictor, pro-inflammatory, and remodelling activities and increased endoplasmic reticular stress and the unfolded protein response in endothelial cells [115]

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(c) they have a lower degree of motivation to quit smoking, low self-efficacy (this term defines the confidence that the subject has in himself to achieve smoking cessation) and their self-esteem levels are decreased4,6,8