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These include diabetes, depression, obesity, mitochondrial dysfunction, metabolic diseases, cell senescence, heart disease among many more

Subsequently, Mahimainathans group identified and validated for the first time a series of miRNAs, miR-153, miR27a, miR142-5p, and also miR-144 in neuronal cells, specifically in human SH-SY5Y neuroblastoma cells, which directly mediate repression of NFE2L2 in a KEAP1-independent manner [224]

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Nat Chem Biol 13:9198 Dixon SJ, Winter GE, Musavi LS, Lee ED, Snijder B, Rebsamen M et al (2015) Human haploid cell genetics reveals roles for lipid metabolism genes in nonapoptotic cell death

Additionally, consuming foods high in vitamin C, such as citrus fruits and strawberries, can help support glutathione production