Sakhaee, Maalouf 2012
IGF-1 LR3 is a modified analog of human Insulin-Like Growth Factor-1, engineered with two structural changes an arginine substitution and a 13-amino acid N-terminal extension that reduce its binding to IGF-1 binding proteins
These neuroprotective effects appear mediated through enhanced cellular autophagy via TFEB nuclear translocation ( Current evidence indicates that curcumin exerts protective effects against epileptic seizures and associated memory impairment, potentially through modulation of brain monoamine levels ( 2.5 Digestive disorders Irritable bowel syndrome (IBS) affects 5%10% of the global population (Staudacher et al., 2023), and frequently co-occurs with stress-related psychiatric disorders such as depression and anxiety (Staudacher et al., 2023)
Dietary calcium may mitigate negative consequences of phosphorus, as a lower ratio of calcium to phosphorus intake appears to increase the chance of negative outcomes, regardless of the level of dietary phosphorus (Uribarri 2013)
Dampened STING-dependent interferon activation in bats
Psychiatry 9 , 110 (2019)
