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kidney and brain tissues
Removal of ubiquitin from a substrate protein occurs via deconjugating enzymes
5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer
which captures the cytokine and presents it to the IL-2Rβ and IL-2Rγ receptors
improves signal to noise by reducing the titer of other reagents in the assay protocol and enables multi-target detection in both IHC and (F)ISH applications
Latrunculin B Animal Cultured Cells kidney and brain tissuesCell permeable marine toxin [1]. Disrupts microfilament mediated processes [2]. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1: 1 complex with monomeric G actin [1, 2, 3]. Depolymerizes actin filaments (F actin) [3]. Less potent than Latrunculin A (Prod. No. AG CN2 0027). May have fewer unwanted effects than latrunculin A and may be preferred for short term studies [4, 5]. Acts via a different mechanism than cytochalasins.