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Medication : Some medications can also affect your B12 levels

DNA repair and genome stability: NAD+-dependent enzymes (PARPs and sirtuins) repair DNA damage, maintaining genetic integrity and reducing mutation risk

Mood improvement: B12 plays a role in producing neurotransmitters that regulate mood, so correcting a deficiency can help alleviate feelings of depression or anxiety that you might not have realized were connected to your B12 status

This finding is mechanistically interesting because there are no published direct links between carnitine and peripheral serotonin synthesis

JoshiRMissongHMishraJKaurSSainiSKandimallaRet al

A blood test can spot a deficiency long before serious symptoms kick in, letting you correct it with targeted support and get your mental sharpness back