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In animal and cell studies, blocking NNMT is theorized to raise intracellular NAD+ and activate SIRT1 , which researchers have linked to fat oxidation and preserved lean mass [1] [2]

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As a result, the richest natural sources are: Shellfish : Clams, oysters, and mussels Fish : Salmon, trout, tuna, and sardines Meat : Beef liver, steak, and poultry Dairy : Milk, yogurt, and cheese Eggs : Particularly the yolk Most people meeting a varied omnivorous diet will achieve adequate intake, but certain diets and digestive issues can impair absorption

Enzymatic activity differs

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See the evidence for tart cherry juice health benefits from clinical studies