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Washington: Motion Picture Association of America, 2012

While you cannot be strictly allergic to pure nicotine, an individual can experience extreme allergic hypersensitivity to the thousands of chemical combustion toxins, acrid gases, and formaldehyde compounds embedded inside burning tobacco smoke clouds

Smokers with a genetic predisposition to autoimmune disorders are at an increased risk of several diseases, including rheumatoid arthritis, Crohns disease, bacterial meningitis, postsurgical infection, and cancers

And there are a lot of them

5 The rate of cigarette smoking among adults in England was around 15% in 2019

Manufacturers Permit Needed for businesses involved in producing tobacco products