Comparison of different types of cell death ACSL4: acyl-CoA synthetase long-chain family member 4, ALOX-15: arachidonate lipoxygenase 15, AP-1: activator protein-1, ATG5: autophagy-related 5, ATG7: autophagy-related 7, COQ10: coenzyme Q10, DRAM3: damage regulated autophagy modulator 3, FSP1: ferroptosis suppressor protein 1, GPX4: glutathione peroxidase 4, HSPB1: heat shock protein beta-1, Keap1: Keleh-like ECH-associated protein 1, MAPK: mitogen-activated protein kinase, MLKL: mixed lineage kinase domain like protein, mTOR: mammalian target of rapamycin, MVA: mevalonate, LC3: microtubule-associated protein 1 light chain 3, NCOA4: nuclear receptor coactivator 4, Nrf2: nuclear factor erythroid 2-related factor 2, PKC: protein kinase C, RIP: receptor-interacting serine/threonine kinase, ROS: reactive oxygen species, SAT1: spermidine/spermine N1-acetyltransferase 1, SLC7A11: solute carrier family 7 member 11, system Xc - : cysteine/glutamate transporter receptor, TFEB: transcription factor EB, TFR1: transferrin receptor 1, TNF-: tumor necrosis factor , TCA cycle: tricarboxylic acid cycle
For molecules that navigate past the OM, the next challenge is retention
PloS Pathog (2012) 8(10):e1002996
The integrity of the BBB model was tested by permeability assays for SF and albumin marker molecules
[DOI] [PMC free article] [PubMed] [Google Scholar] 140
Her current research focuses on mechanistic study of immune-mediated drug toxicity by investigating drug metabolism and drugprotein interaction/adduct using advanced mass spectrometric methods
