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While many people get sufficient amounts through diet or supplementation, some individuals require more direct forms of administrationsuch as injectionsdue to medical conditions or absorption issues
doi: 10.1073/pnas.82.20.6955, 61 LangS
81 It also slows stomach emptying, which helps control appetite and reduce food intake
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Oral supplements must first pass through the digestive tract, where a portion of the active compound can be degraded or poorly absorbed, especially if gastrointestinal issues are present