Mortality was 17.2% in the Gln group, which was not significantly different from 16.2% in the placebo group, and Gln supplementation did not reduce the length of hospital stay
Statistical test Data were subjected to analysis of variance (ANOVA) and Tukey's honestly significant difference (HSD) multiple comparisons were conducted using ProStat software Version 5.5(Poly Software International Inc., Pearl River, NY)
Some inherited metabolic disorders (pyridoxine-dependent conditions) may require very large daily doses
This raises an intriguing question of whether alternative sources of energy, such as ketone bodies by-passing the glycolytic pathway, might lead to increases in energy, and indeed some studies showed a reduction in fatigue in ME/CFS on a ketone diet [80]
Heres what the research shows it can do: Stimulate new blood vessel growth to injured areas (angiogenesis) Accelerate healing in tendons, ligaments, and connective tissue Reduce inflammation without suppressing immune function Protect nerve cells and support nerve regeneration Promote cartilage repair and joint tissue recovery The anti-inflammatory effect without immune suppression is particularly notable
Why Medical Experts Continue to Urge Caution Despite growing interest, several important limitations remain