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D. C. Morris, M. Chopp, L. Zhang, and Z. G. Zhang, Thymosin 4: a candidate for treatment of stroke?, Wiley, May 2010. doi: 10.1111/j.1749-6632.2010.05469.x

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Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence

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The most methodologically sound approach is staggered introduction: start MOTS-c alone for 1014 days to establish baseline metabolic response, then add 5-Amino-1MQ at starting dose and monitor for synergistic effects over the following 1421 days