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If you or a first-degree relative has been diagnosed with these conditions, do not use tirzepatide

Scientific findings on using B12 for weight loss have mixed results

B12 Injections are particularly effective for individuals experiencing: Fatigue : Constant tiredness that does not improve with rest

The Pernicious Anaemia Society notes this is well documented but poorly understood, and that some patients self-inject more frequently

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The rationale is that AOD 9604 preferentially targets adipose tissue, which might help shift the composition of weight loss more toward fat and away from lean mass