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In fact, many prominent ASD risk genes encode histone methyltransferases and demethylases, such as euchromatic histone lysine methyltransferase 1 (EHMT1), lysine methyltransferase 2C (KMT2C), and lysine-specific demethylase 1 (LSD1) [91]

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Published in 1970, their research confirmed the existence of GIP (Brown, Mutt, Pederson)

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