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As stated in, the treatment of oral squamous cell carcinoma (OSCC) with iron death inducer (PL) has been shown to result in lipid peroxidation (LPO) and intracellular ROS accumulation, accompanied by a decrease in the expression of FTH1, SLC7A11, and GPX4

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Its collagen-stimulating properties are well-documented: tretinoin increases type I and type III procollagen synthesis in photodamaged skin, partially restoring the dermal collagen network that breaks down with chronic UV exposure

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