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A 2003 prospective cohort study by Khavinson and Morozov found that epithalon had the following effects when administered to a sample of 266 adults over the age of 60 [9]: Decreased incidence of ischemic heart disease Decreased incidence of hypertension disease Lowered rates of deforming osteoarthritis and osteoporosis More recently, a 2020 study by Khavinson et al

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Biochem J 320:100510, PMID: 9003392 Nikulina MA, Andersen HU, Karlsen AE, Darville MI, Eizirik DL, Mandrup-Poluson T (2000) Glutathione depletion inhibits interleukin 1 beta-stimulated nitric oxide production by reducing inducible nitric oxide synthase gene expression

Fc also binds to FcRs on the surface of DCs and connects them to T cells to activate T cells [197]

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