Causes of mouth ulcers Most single mouth ulcers are caused by things you can try to avoid, such as: biting the inside of your cheek badly fitting dentures, braces, rough fillings or a sharp tooth cuts or burns while eating or drinking for example, hard food or hot drinks a food intolerance or allergy damaging your gums with a toothbrush or irritating toothpaste feeling tired, stressed or anxious Sometimes they're triggered by things you cannot always control, such as: hormonal changes such as during pregnancy your genes some families get mouth ulcers more often a vitamin deficiency, such as iron, zinc, folic acid, vitamin B or vitamin D medicines including some NSAIDs, beta blockers or nicorandil stopping smoking people may develop mouth ulcers when they first stop smoking If you have several mouth ulcers, it can be a symptom of: hand, foot and mouth disease, which also causes a rash on the hands and feet oral lichen planus, which causes a white, lacy pattern inside the cheeks Crohn's disease and coeliac disease (conditions that affect the digestive system) a weakened immune system from having a condition like HIV or lupus Page last reviewed: 11 March 2024 Next review due: 11 March 2027

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