does tobacco cause memory loss under siege: the cognitive costs of smoking and vaping Smoking is associated with impaired

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JAMA 311(2):135136

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For example, the pleasurable effects of alcohol use could be mediated by release of dopamine and opioids in the mesolimbic forebrain, while the anxiolytic effects could reflect facilitation of brain gamma-aminobutyric acid (GABA) activity (Lingford-Hughes et al., 2010)

Compared with CC only users, the AOR (95% CI) for the first tobacco product uses within 30 minutes of waking up was 1.64 (1.162.30) for HTP only users, 1.62 (1.262.08) for dual users of CCs + HTPs, 2.61 (1.474.63) for dual users of ECs + HTPs, and 2.04 (1.532.73) for triple users

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