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One does need to increase the dosage slowly, titrating it, under monitoring TSH levels and most importantly, monitoring the patients well-being. Thyroid hormones in excess carry the risk of tachycardia and arrhythmia that is why usually the prohormone T4 and not the active hormone T3 is prescribed and supplemented

Fresh tissue damage still has the cellular machinery for repair actively engaged, while chronic injuries may have entered a degenerative plateau

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doi:10.1002/14651858.CD010287.pub3 Tsiami AP, Goulis DG, Sotiriadis AI, Kolibianakis EM

They see IV vitamin therapy as a luxury, not a necessity

Mitochondrial damage triggers intracellular surveillance mechanisms that promote encapsulation of impaired mitochondria by autophagosomes 37