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A review of eight randomized controlled trials, which included 761 patients with solid tumors, showed that 20 mg of melatonin per day significantly reduced chemotherapy-related side effects, including fatigue

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That move cut off access for patients who had been using them and created the gray market that now dominates online searches

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doi: 10.3390/molecules26226949 18 LugrinJRosenblatt-VelinNParapanovRLiaudetL