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Secondary Outcome : Safety, tolerability, and adverse effects

Characterization of VDAC1 as a plasma membrane NADH-oxidoreductase

This process is critical for neuronal survival, and the lack of such control has been reported to result in neurodegeneration in mice 87

Research into CAFs has surged over the past decade, greatly advancing our understanding of their roles in the TME and potential as therapeutic targets

In this paper, we initially focused on uncovering the mechanism of action of DPI, a NADPH oxidase inhibitor that we previously found to specifically inhibit MNA NB cell proliferation (56, 57)

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