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Ang II produces RONS by stimulating membrane-bound NADPH oxidase [53, 54]

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According to arrhythmic profile, the slightest decrease was exhibited in paroxysmal supraventricular tachycardia, for both groups (73.90% for patients in group I and 82.37% for group II) and the most significant decrease was revealed in sinus bradycardia (64.66%), in the dyslipidemia group and also in atrial flutter (66.58%) in non-dyslipidemics, all compared with the control group

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In response to different extracellular stimuli, the complex may dissociate and JNK can phosphorylate c-Jun, a component of the activator protein-1 transcription factor

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