Festival de Cannes
10.15252/embj.2018100041
3.3.5.3 Dietary interventions Dietary strategies such as tryptophan supplementation may exert anxiolytic effects through gut brain axis
Current research has significantly explored the bidirectional relationship between dysregulated brain metabolism and sleep impairments in influencing aging as well as age-associated neurocognitive deficits, and suggests that alterations in any one of them exacerbate the other, leading to accelerated aging and neurodegeneration ( vice versa , since impaired glucose utilization, lipid metabolism as well as oxidative stress in the mitochondria, are altered as we age and conversely, exacerbated ROS and a decline in bioenergetics in neuroglial cells, aggravates aging and cognition (Srivastava, 2017)
Gonzalez F, Rote NS, Minium J, Kirwan JP: Reactive oxygen species-induced oxidative stress in the development of insulin resistance and hyperandrogenism in polycystic ovary syndrome
Many of its effects are mediated through a hormone called IGF-1 (Insulin-Like Growth Factor 1) , which is primarily produced in the liver in response to GH signaling
