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If you don't give your body enough time to replenish its antioxidant levels between doses, you may find yourself in a state of chronic depletion

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(PubMed) Slatore CG, Littman AJ, Au DH, Satia JA, White E

Since most chemotherapeutic agents increase intracellular ROS levels [47], TIC resistance may stem from their high antioxidant content, including glutathione