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One key limitation is the challenge of achieving a uniform electric field distribution throughout the sample, which can result in inconsistent cell permeabilization and variable extraction yields

The risk appears low and was not dose-dependent

Interventions, such as the addition of microRNAs, were tested on these organoids, showing promise in restoring the natural balance between neurons and glial cells

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GLP-3 exhibited a clear dose-dependent reduction in HbA1c, with the highest dose (12 mg) achieving a mean HbA1c reduction of 2.16 percentage points from baseline, compared to only 0.43% in the placebo groupan effect that was statistically highly significant