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In the forebrain, approximately 20% of synoptically released glutamate reaches the postsynaptic glutamate receptors from the synaptic cleft during synaptic transmission, and the remainder can reach the astrocytes for glutamate re-uptake [170]

Activated microglia decrease histone acetylation and Nrf2-inducible anti-oxidant defence in astrocytes: restoring effects of inhibitors of HDACs, p38 MAPK and GSK3

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[9] These are legitimate, informative animal studies about the compounds mechanism and pharmacology

In yeast, PUS7p deficiency has been shown to reduce the stability of -containing transcripts during heat shock [100]