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Therapeutic implications Therapeutic strategies for APAP-induced liver injury involve mitigating inflammation, preventing hepatocyte death, and promoting liver regeneration

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This peptide has also not been approved by the FDA for human consumption and should be used for research purposes only

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To validate the candidate genes from CRISPR-Cas9 knockout screening, the top two sgRNAs for each candidate gene, one positive control (sgRNA targeting GGCX), and one negative control (non-targeting sgRNA) were individually cloned into the lentivirial plasmid backbone lentiCRISPR v2 which contains the Cas9 component