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17 A key characteristics of pain related to IC/BPS is that the pain is worsened with bladder filling (painful bladder filling) and/or their strong urge to urinate was due to pain, pressure, or discomfort (painful urgency)

Results: Vitamin B12 supplementation was associated with a significant increase in serum cobalamin levels across all routes of administration (pooled mean difference = +402.6 pg/mL

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NAD therapy should not replace proven addiction treatments, such as behavioral therapy, counseling, or medication-assisted treatment when appropriate

Thus, given these findings together, it can be an argument analogy between the BPC 157 presentation and the presentation of serotonin, which is most commonly acknowledged [166]

doi: 10.1523/JNEUROSCI.1380-11.2011