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doi: 10.1038/s41585-020-0288-x 26 RajagopalanKNMarianCOShayJWDeBerardinisRJ

Early research showed they didn't do much to increase glutathione levels or improve skin radiance

Xu et al., CD44 correlates with clinicopathological characteristics and is upregulated by EGFR in breast cancer

Gastrointestinal Problems Some people have reported nausea, bloating, and abdominal pain after taking huge doses of glutathione

As we age, we lack key amino acids needed to build glutathione, and can suffer from glutathione deficiency