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The trial included 60 adult participants (mean age approximately 49) who had clinical follow-up with labs every 2 months for up to 2 years, with some withdrawing early due to spontaneous remission, indication for definitive therapy (e.g., thyroidectomy or radioiodine), or an intolerance to the treatment

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Using qRT-PCR, relative CAP1 and TRR1 mRNA levels were measured relative to the internal ACT1 mRNA control in C