In vitro, uric acid is a powerful scavenger of ROS32 and by being preferentially oxidized as a substrate for oxidation by haem protein or H2O2 systems, it can protect against oxidative damage.33 As marker of oxidative stress, the GSH/GSSG ratio was determined in both duodenal and sigmoid biopsies
While it is true that glutathione can help improve skin complexion, it is also an essential antioxidant that plays a vital role in detoxifying the body, boosting the immune system, and protecting cells from damage caused by free radicals
In models of chronic stress-induced depression, swimming has been shown to reduce serum corticosterone (CORT) levels and proinflammatory cytokines (IFN-, TNF-), while simultaneously increasing serotonin levels in the prefrontal cortex, reinforcing its antidepressant effects [93]
Mitochondria-targeted antioxidants, including MitoQ and SS31, may serve as potential therapeutic agents that reduce free radicals, maintain mitochondrial quality and function, enhance autophagy and mitophagy, and help cells remove damaged mitochondria [24, 31]
Rheumatoid Arthritis - Common Origins, Divergent Mechanisms
Natural antioxidants found in plants are generally responsible for preventing or slowing the harmful effects of oxidative stress (OS), which is considered the root cause of aging and various human diseases such as AS, stroke, HTN, DM, cancer, and neurological disorders (37)
