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In contrast, removal of insulin receptors from somatotrophs leads to an increase in the content and release of GH in the pituitary [155]

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10.3109/09513590.2010.491925 Gynecol

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Febs Lett

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Therefore, the problem that the agents successful in pre-clinical experimental autoimmune encephalitis trials, were either less effective in patients, worsened disease or caused unexpected, severe adverse events (60), may be at least partly solved with the more suited cuprizone model that reflects a toxic experimental model (12)

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[Updated 2022 Sep 19]

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Emerging research demonstrates that the mitochondrial quality control (MQC) system maintains cellular homeostasis through coordinated processes including mitochondrial biogenesis, mitophagy, and mitochondrial dynamics (fission/fusion)

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