Yes lyophilised GHK-Cu stored for longer than 6 months shows 34 times higher aggregation rates compared to freshly synthesised batches, even when stored at 20C
It was observed that metabolites such as dihydroxy phenylacetic acid, butyrate, adenosine, propionate, histamine, norepinephrine, acetate, GABA, 5-hydroxy indole acetic acid, valerate, tryptophan, and aspartic acid were decreased and caproate, serotonin 3-methyl valerate, and acetylcholine were increased upon tumour growth [236]
10.1089/ars.2013.5236 70 WangQ.ZhanS.LiuY.HanF.ShiL.HanC.et al (2021)
Fish were fed twice a day with commercial flaked food (Alcon Basic, Alcon, Cambori, Brazil)
These points need further investigation
Heme oxygenase-1 belongs to the heat-shock protein family, which is a rate-limiting microsomal enzyme involved in heme catabolism