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Throughout this proposed rule, and in the context of the word cause or causes used in the textual warning statements included therein, FDA relied on the four-level classification provided in the Surgeon General's Reports

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Feeling anxious without an apparent trigger typically means your body is responding to internal stress rather than external threats

Clin Exp Immunol

While chronic bronchitis (excessive mucus production and cough) and emphysema (alveolar damage leading to reduced gas exchange) are commonly described phenotypes, many patients exhibit features of both, reflecting a combined disease presentation rather than distinct subtypes 4,5

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