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What is the bioavailability of GHKCu when given by subcutaneous injection versus topical application?

[DOI] [PMC free article] [PubMed] [Google Scholar] 32.Aw TY, Wierzbicka G, Jones DP

demonstrated that exogenous IGF-1 administration reduces functional deficits and accelerates recovery in a rat Achilles tendon injury model ( In vitro studies further support its therapeutic potential, showing that IGF-1 modulates inflammatory responses, stimulates tenocyte proliferation and migration, and enhances collagen synthesis (Olesen et al., 2021)

The researchers suggest that these actions may be due to the presence of a GHK triplet in the alpha 2(I) chain of type I collagen

Ilic S, Brcic I, Mester M, Filipovic M, Sever M, Klicek R, et al

DAX-1 (Dosage-sensitive sex reversal, Adrenal hypoplasia congenital critical region on the X chromosome, gene 1) is a transcription factor expressed in the adrenal gland and gonads