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& Huang, S

Targeting the S1P/S1PR1 axis mitigates cancer-induced bone pain and neuroinflammation

We found that the gastrocnemius wet weight ratio in the SCI group was significantly decreased at 4 and 8 weeks compared with that in both the control and GlyNAC+SCI groups

Moreover, the ability of the immune system (mainly CTLs) to recognize HBV-infected hepatocytes is substantially limited by alcohol exposure at the level of MHC-I restricted antigen presentation on target hepatocytes (63)

This protonation introduces positive charges that can disrupt electrostatic interactions or cause steric clashes within the antigen-antibody binding interface, thereby reducing binding affinity specifically at low pH [74]

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