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Intranasal administration has been shown in animal and some early human work to cross into the system and produce measurable effects on sleep-related endpoints

It also has been described that -glutamylcysteine, the intermediate of GSH biosynthesis, is able to act as a Gpx1 cofactor in mitochondrial H 2 O 2 detoxification, mimicking the physiological properties of GSH (Quintana-Cabrera et al., 2012)

dopamine-, NO-, somatosensory neuronal-system) which manifest either over-activity or as inhibition, may contribute to the multiple lesions in different organs

Claesson MJ, Cusack S, OSullivan O, Greene-Diniz R, de Weerd H, Flannery E, Marchesi JR, Falush D, Dinan T, Fitzgerald G, et al

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Age, sex and post-mortem interval were included as covariates, and controlled for in the regression analysis