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Unaffected individuals from both cohorts obtained from Kahemba were not considered to have konzo at the time of sampling following the 3 main criteria for diagnosis outlined by the World Health Organization

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Generally, lactylation affects the activity of RNA modification-related enzymes by enhancing transcription activation via histone Kla or directly lactylating these enzymes, eventually regulating RNA modification (Fig

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Active B12 assay for diagnosing vitamin B12 deficiency (MIB40) NICE