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Downregulation of key constituents controlling mitochondrial biogenesis in peripheral lung tissue from very severe COPD patients To evaluate if, and to what extent, the pathways regulating mitochondrial turnover (biogenesis versus breakdown of mitochondria) are affected in peripheral lung tissue from COPD patients, we first investigated the mRNA expression of molecules involved in the regulation of mitochondrial biogenesis

Women who dont smoke but are exposed to secondhand smoke during their pregnancy may also give birth to babies with lower birth weight

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In addition to the huge human toll of illness and death there is the enormous cost to the global economy

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Galectin-8 also modulates a number of known inflammatory pathways, modulating cell adhesion, promoting apoptosis and inducing senescence 20,21,22