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It supplies the mechanistic and directional rationale for the whole compound class, but it is not a human trial and does not establish a human dose

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These lasting benefits can persist for several weeks or months, especially when B12 shots are part of a regular supplementation routine

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Garvey WT et al., SURMOUNT-2, Lancet 2023 : tirzepatide in obese diabetic patients with type 2 diabetes

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