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Vanden Berghe, T

The mutant BRAF exhibits constitutive activation of its kinase activity, leading to hyperactivation of MAPK signaling, which results in uncontrolled proliferation and metastasis

Mplan C, Crosley LK, Nicol F, Horgan GW, Mathers JC, Arthur JR, Hesketh JE

A Meisel: received speaker honoraria from Alexion, argenx, Axunio, Boehringer Ingelheim, Bristol-Myers Squibb/Pfizer, Grifols, and Hormosan

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