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As the global glutathione market expands across pharmaceuticals, nutraceuticals, and cosmetics, this tripeptide has emerged as a core bioactive ingredient fueled by consumer demand for antioxidant, detoxification, and restorative effects

Mechanical hyperalgesia may also be caused by centrally amplifying responses

However, intravenous use can cause redness, itching, and irritation at injection sites

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Candidate drugs are in development for treatment of sarcopenic obesity, often a disease of aging and defined by the coexistence of obesity and sarcopenia 68

These observations support the continued study of GHK-Cu as a peptide metal complex involved in extracellular matrix-related signaling and regenerative pathway modulation