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Free Radic Biol Med 2015

Curcumin blocks IB kinase inhibitor of B kinase (IKK) activity, preventing the degradation of IB and the translocation of NF-B to the nucleus, leading to downregulation of NF-B dependent genes involved in cell growth and survival, such as cyclin D1, COX-2, and Bcl-2 family proteins (Plummer et al., 1999

[DOI] [PubMed] [Google Scholar] 81.Baiceanu E., Nguyen K.A., Gonzalez-Lobato L., Nasr R., Baubichon-Cortay H., Loghin F., Le Borgne M., Chow L., Boumendjel A., Peuchmaur M., et al

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Biophys J 85(3):14211428

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