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A physician-supervised protocol that takes muscle preservation seriously addresses it through three non-negotiable pillars: Protein : approximately 1 g per pound of lean body mass daily, maintained consistently even when appetite is significantly suppressed Branched-chain amino acids : leucine in particular directly suppresses catabolism signalling at the source rather than just providing substrate
Rev Neurol (Paris) 172(1):313 Lokovic BV, Gottesman RF, Bernstein KE, Seshadri S, McKee A, Snyder H, Greenberg SM, Yaffe K, Schaffer CB, Yuan C, Hughes TM, Daemen MJ, Williamson JD, Gonzlez HM, Schneider J, Wellington CL, Katusic ZS, Stoeckel L, Koenig JI, Corriveau RA,, Chen J (2020) Vascular contributions to cognitive impairment and dementia (VCID): a report from the 2018 national heart, lung, and blood institute and national institute of neurological disorders and stroke workshop