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In a clinical study, participants orally consumed

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Acta Trop 140:105117

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Polymorphism analysis of six selenoprotein genes: support for a selective sweep at the glutathione peroxidase 1 locus (3p21) in Asian populations

TPN, in which all nutrition is delivered intravenously, is frequently associated with rapid weight loss and lack of gallbladder stimulation, both of which can contribute to gallstone formation (Shaffer 2018)