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Paradigm shift in NMDA receptor antagonist drug development: molecular mechanism of uncompetitive inhibition by memantine in the treatment of Alzheimers disease and other neurologic disorders
doi: 10.1021/jf00107a049
Antioxidants protect your cells from oxidative stress caused by free radicals
Nevertheless, it was assumed that the spectrum of compounds evaluated was sufficiently broad to encompass the main non-regulated mycotoxins of relevance
63,244,245 Incorporating the covalent warheads into proteolysis-targeting chimeras (PROTACs) that enhance the degradation of disease-related proteins of interest (POIs) has led to revolutionary therapeutics to tackle POIs previously considered as undruggable
Similarly, melatonin was used as an adjuvant for the prevention of POF during chemotherapy (184, 185), given its experimentally proven role in the female reproductive tract (186)
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